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A Pakistan-registered cargo plane has gone missing off the coast of Karachi following a navigation issue. The aircraft, operated by a local airline, disappeared from radar approximately 150 kilometers from the port city. Authorities have launched a search and rescue operation involving maritime and air units. The incident has raised concerns about aviation safety in the region, particularly for cargo operations in the Arabian Sea. While no immediate financial market implications are reported, the event could indirectly affect regional trade routes and insurance costs for maritime and air cargo. Investors may monitor updates on the search operation and potential regulatory responses from aviation authorities.